Authors: Miranda-Massari JR, Toro AP, Loh D, Rodriguez JR, Borges RM PMID: 34947872 PMCID: PMC8708699 DOI: 10.3390/life11121341 Abstract Currently available anti-viral drugs may be useful in reducing the viral load but are not providing the necessary physiological effects to reduce the SARS-CoV-2 complications efficiently. Treatments that provide better clinical outcomes are urgently needed. Vitamin C [...]

Authors: Neil M, Fenton N, Smalley J, Craig C, Guetzkow J, Rose J DOI:10.13140/RG.2.2.14176.20483 Abstract The risk/benefit of Covid vaccines is arguably most accurately measured by an all-cause mortality rate comparison of vaccinated against unvaccinated, since it not only avoids most confounders relating to case definition but also fulfils the WHO/CDC definition of "vaccine effectiveness" [...]

Authors: Mohabatkar H, Behbahani M, Moradi M doi: https://doi.org/10.15414/jmbfs.4813 Abstract COVID-19 has shown higher virulence compared to the previous coronavirus epidemics and has shown that it causes damages to the nervous system. In the present study, PrionW web server was used to predict the prion-like domains (PrLDs) in 15 structural and nonstructural proteins of SARS-CoV, [...]

Authors: Kiprov DD, Herskowitz A, Kim D, Lieb M, Liu C, Watanabe E PMID: 35464182 PMCID: PMC9021669 DOI: 10.12688/f1000research.74534.2 Abstract Many patients with COVID-19 experience a range of debilitating symptoms months after being infected, a syndrome termed long-haul COVID. A 68-year-old male presented with lung opacity, fatigue, physical and cognitive weaknesses, loss of smell and [...]

Authors: Abrams RM, Simpson DM, Navis A, Jette N, Zhou L PMID: 34766365 PMCID: PMC8661991 DOI: 10.1002/mus.27458 Abstract Introduction/aims: The development and persistence of neurological symptoms following severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection is referred to as "long-haul" syndrome. We aimed to determine whether small fiber neuropathy (SFN) was associated with SARS-CoV-2 infection. [...]

Authors: Robbins T, Gonevski M, Clark C, Sharma K, Magar A PMID: 34862223 PMCID: PMC8806311 DOI: 10.7861/clinmed.2021-0462 Abstract Background: Long COVID is a common occurrence following COVID-19 infection. The most common symptom reported is fatigue. Limited interventional treatment options exist. We report the first evaluation of hyperbaric oxygen therapy (HBOT) for long COVID treatment. Methods: [...]

Authors: Ndeupen S, Qin Z, Jacobsen S, Bouteau A, Estanbouli H, Igyarto BZ PMID: 34841223 PMCID: PMC8604799 DOI: 10.1016/j.isci.2021.103479 Abstract Vaccines based on mRNA-containing lipid nanoparticles (LNPs) are a promising new platform used by two leading vaccines against COVID-19. Clinical trials and ongoing vaccinations present with varying degrees of protection levels and side effects. However, [...]

Authors: Thomas R, Aldous J, Forsyth R, Chater A, Williams M. DOI: 10.29011/2577-1515.100182 Abstract Background: Gut microfloral dysbiosis is known to affect the majority individuals suffering with a Covid-19 infection. This study evaluated whether a specific lactobacillus and inulin blend, which aimed to improve gut health, could reduce the severity of early and chronic Covid-19 [...]

Authors: Holford P, Carr AC, Zawari M, Vizcaychipi MP PMID: 34833042 PMCID: PMC8624950 DOI: 10.3390/life11111166 Abstract Severe respiratory infections are characterized by elevated inflammation and generation of reactive oxygen species (ROS) which may lead to a decrease in antioxidants such as vitamin C and a higher requirement for the vitamin. Administration of intravenous vitamin C [...]

Authors: Olajide O, Iwuanyanwu VU, Adegbola OD, Al-Hindawi AA PMID: 34709564 PMCID: PMC8551352 DOI: 10.1007/s12035-021-02593-6 Abstract In addition to respiratory complications produced by SARS‐CoV‐2, accumulating evidence suggests that some neurological symptoms are associated with the disease caused by this coronavirus. In this study, we investigated the effects of the SARS‐CoV‐2 spike protein S1 stimulation on [...]