Authors: Thimmulappa RK, Mudnakudu-Nagaraju KK, Shivamallu C, Bhojraj S. PMID: PMC7899028 doi: 10.1016/j.heliyon.2021.e06350 Abstract Coronavirus disease-19 (COVID-19), a devastating respiratory illness caused by SARS-associated coronavirus-2 (SARS-CoV-2), has already affected over 64 million people and caused 1.48 million deaths, just 12 months from the first diagnosis. COVID-19 patients develop serious complications, including severe pneumonia, acute respiratory [...]

Authors:Vogel-Gonzalez M, Tallo-Parra M, Herrera-Fernandez V, Perez-Vilaro G. PMID: PMC7914437 DOI: 10.3390/nu13020562 Abstract Background: Zinc is an essential micronutrient that impacts host-pathogen interplay at infection. Zinc balances immune responses, and also has a proven direct antiviral action against some viruses. Importantly, zinc deficiency (ZD) is a common condition in elderly and individuals with chronic diseases, [...]

Stay-at-home orders, physical distancing, face masks and other non-pharmaceutical interventions (NPIs) do not only impact COVID-19, but also the dynamics of various other infectious diseases. Bronchiolitis is a clinically diagnosed viral infection of the lower respiratory tract, and causes a yearly seasonal wave of admissions in paediatric wards worldwide. We counted 92,5% less bronchiolitis hospitalisations in Antwerp before the expected end of the peak this year (of which only 1 RSV positive), as compared to the last 3 years. Furthermore, there was a >99% reduction in the number of registered RSV cases in Belgium.Conslusion: The 2020 winter bronchiolitis peak is hitherto nonexistent, but we fear a 'delayed' spring/summer bronchiolitis peak when most NPIs will be relaxed and pre-pandemic life restarts. What is known? • Bronchiolitis causes a yearly seasonal wave of admissions in paediatric departments worldwide. • Non-pharmaceutical interventions (NPIs) do not only impact COVID-19, but also the dynamics of various other infectious diseases. What is new? • The 2020 winter bronchiolitis peak is hitherto nonexistent. • A 'delayed' spring or summer bronchiolitis peak could happen when most NPIs will be relaxed and pre-pandemic life restarts.

Authors: Saeedi-Boroujeni A, Mahmoudian-Sani MR. PMID: Abstract SARS-CoV-2 is a betacoronavirus causing severe inflammatory pneumonia, so that excessive inflammation is considered a risk factor for the disease. According to reports, cytokine storm is strongly responsible for death in such patients. Some of the consequences of severe inflammation and cytokine storms include acute respiratory distress [...]

Authors: Jena AB, Kanungo N, Nayak V, Chainy GB. PMID: PMC8043087 DOI: 10.1038/s41598-021-88218-3 Abstract The recent outbreak of the coronavirus (SARS-CoV2) is an unprecedented threat to human health and society across the globe. In this context, development of suitable interventions is the need of the hour. The viral spike protein (S Protein) and the cognate [...]

Authors:Shakoor H, Feehan J, Dhaheri AS, Ali HI, Platat C, Ismail LC. PMID:PMC7415215 DOI: 10.1016/j.maturitas.2020.08.003 Abstract The world is currently in the grips of the coronavirus disease (COVID-19) pandemic, caused by the SARS-CoV-2 virus, which has mutated to allow human-to-human spread. Infection can cause fever, dry cough, fatigue, severe pneumonia, respiratory distress syndrome and in [...]

Authors: Yeoh YK, Zuo T, Lui GC, Zhang F, Liu Q. PMID: 33431578 PMCID: PMC7804842 DOI: 10.1136/gutjnl-2020-323020 Abstract Objective: Although COVID-19 is primarily a respiratory illness, there is mounting evidence suggesting that the GI tract is involved in this disease. We investigated whether the gut microbiome is linked to disease severity [...]

Authors: Choudhury IM, Shabnam N, Ahsan T, Kabir S, Ahsan SM. DOI: https://doi.org/10.3329/brc.v7i1.54245 Abstract Background: The sudden onset of COVID-19 began in late 2019 caused by a novel coronavirus (SARS-COV2) and on 11th March, WHO declared it to have developed pandemic status. There is still no specific treatment and vaccine available for COVID-19; causing wide [...]

Authors: Tahmasebi S, El-Esawi MA, Mahmoud ZH, Timoshin A, Vaez A, Aslani S. PMID: 33372280 DOI: 10.1002/jcp.30233 Abstract In novel coronavirus disease 2019 (COVID-19), the increased frequency and overactivation of T helper (Th) 17 cells and subsequent production of large amounts of proinflammatory cytokines result in hyperinflammation and disease progression. The current study aimed to [...]

Authors: Cangiano B, Fatti LM, D anesi L, Croci M, Vitale G. PMID: PMC7803543 DOI: 10.18632/aging.202307 Abstract Introduction: The COVID-19 pandemic caused an increased mortality in nursing homes due to its quick spread and the age-related high lethality. Results: We observed a two-month mortality of 40%, compared to 6.4% in the previous year. This increase [...]